The vascular endothelial growth factor (VEGF) family of cytokines are key drivers of blood vessel growth and remodeling. These ligands act via multiple VEGF receptors (VEGFR) and co-receptors such as Neuropilin (NRP) expressed on endothelial cells. These membrane-associated receptors are not solely expressed on the cell surface. they move between the surface and intracellular locations. https://www.rivervalleydanceac.com/product-category/pherrowscap/
Trafficking dynamics of VEGFR1, VEGFR2, and NRP1 in human endothelial cells.
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