Extrachromosomal DNAs (ecDNAs) are a pervasive feature found in cancer and contain oncogenes and their corresponding regulatory elements. Their unique structural properties allow a rapid amplification of oncogenes and alter chromatin accessibility. leading to tumorigenesis and malignant development. The uneven segregation of ecDNA during cell division enhances intercellular genetic he... https://poolsproductscanadas.shop/product-category/jandy-aqualink-z4-parts/